Beta
ManageSearchChatDiscover
315297

Validation of Lyophilized-Attenuated Single and Combined Canine Hepatitis, Canine Distemper, and Canine Parvovirus Vaccines

Article

Last updated: 24 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Through this study, we attempted to prepare and evaluate lyophilized attenuated single and trivalent vaccines of Canine Distemper (CD), Canine Adeno-1 (CA-1), and Canine Parvo (Cp type 2a) viruses. All such preparations were found to be free from foreign contaminants, safe in mice and puppies, and potent, providing vaccinated puppies with good levels of specific antibody titers against the three viruses as estimated by serum neutralization test (SNT) and indirect immune sorbent assay (ELISA). Such antibodies were found to be stable up to 12 months post-vaccination, supporting their use to protect puppies against the three virus infections with the preferable use of the trivalent vaccine, which saves effort and avoids stress factors of vaccinated puppies.

DOI

10.5455/djvs.2021.80072.1039

Keywords

canine distemper, Canine Adeno-1, canine parvo, single vaccines, combined vaccines, serum neutralization, ELISA

Authors

First Name

Asmaa

Last Name

Abdel-Samad

MiddleName

Gamal

Affiliation

Agriculture Research Center (ARC); Veterinary Serum and Vaccine Research Institute (VSVRI), Abasia, Cairo, Egypt

Email

asmaagamal223@yahoo.com

City

-

Orcid

-

First Name

Nabil

Last Name

Bkear

MiddleName

Mohamed

Affiliation

Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt

Email

-

City

-

Orcid

-

First Name

Adel

Last Name

Khadr

MiddleName

Mohamed

Affiliation

Faculty of Veterinary Medicine, Alexandria University, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

Khodier

MiddleName

Hassan

Affiliation

Agriculture Research Center (ARC); Veterinary Serum and Vaccine Research Institute (VSVRI), Abasia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Samir

Last Name

Edries

MiddleName

Mohamed

Affiliation

Agriculture Research Center (ARC); Veterinary Serum and Vaccine Research Institute (VSVRI), Abasia, Cairo, Egypt

Email

-

City

-

Orcid

-

Volume

10

Article Issue

1

Related Issue

41345

Issue Date

2023-07-01

Receive Date

2021-06-10

Publish Date

2023-07-01

Page Start

25

Page End

30

Print ISSN

2636-3003

Online ISSN

2636-3011

Article File

DJVS_Volume 10_Issue 1_Pages 25-30.pdf

PDF . 293.0kB

Link

https://djvs.journals.ekb.eg/article_315297.html

Detail API

https://djvs.journals.ekb.eg/service?article_code=315297

Order

315,297

Type

Original Article

Type Code

1,001

Publication Type

Journal

Publication Title

Damanhour Journal of Veterinary Sciences

Publication Link

https://djvs.journals.ekb.eg/

MainTitle

Validation of Lyophilized-Attenuated Single and Combined Canine Hepatitis, Canine Distemper, and Canine Parvovirus Vaccines

Details

Type

Article

Created At

24 Dec 2024