In the digital and industry 4.0 era, data is very valuable precious. All sectors, both industry and education need data as a source of information and insight into improving quality. Technology and information systems are growing so that the amount of data that can be processed is very large and fast. Those phenomena are called big data. In the pandemic era, the use and utilization of big data in education are very significant and determine the learning process. To obtain meaningful information in decision-making, big data analytics is needed. In addition, another important aspect is data science. As a distance education institution, Universitas Terbuka has a high opportunity to apply and offer data science courses. The prospect of being a data scientist is very high and it occupies a prestigious position in the modern world. This article explains big data, big data analytics, and data science and its prospects at Universitas Terbuka. These three parts are interconnected and needed in the digital and industry 4.0 era.