For enhancing the human thermal comfort and lessening environmental effect, cooling of outdoor air with water misting is suggested as a way to improve performance during hot weather. This helps to create sustainable solutions. To find out the impact of various misting system characteristics, a parametric analysis study was carried out including the distance between nozzles (from 5 m to 17 m – three cases) and the number of nozzles (from 3 nozzles to 5 nozzles – three cases), along with changing the distance between nozzles along x-axis (from 0.6 m to 1.2 m – four cases). In the current study, a CFD technique was used to study 3D simulations. Discrete Phase Model (DPM) was used for calculating momentum, heat and mass exchange between the water mist and the air. The results showed that, the most successful cases at the following: (1) the distance between nozzles (∆Z = 17 m), and (2) the number of nozzles (N = 4 nozzles). Which achieves temperature and relative humidity: (1) 31.56 ℃ & 65.58%, (2) 31.53 ℃ & 65.69%, respectively. Moreover, it's observed that the best case when the distance between nozzles along x-axis (d = 0.8 m) which achieves 31.00 ℃ and 67.00% of RH.