This study was conducted on 40 one-day-old broiler chicks for five weeks to investigate the influence of magnetic water and yeast supplementation (Saccharomyces cerevisiae) on growth performance, hematological parameters, some serum biochemical parameters, oxidative stress, and antioxidant, as well as some inflammatory markers. The chicks were divided into four equal groups, as follows: GI: free from water additives, G II:  supplied with magnetic water, G III: supplied with yeast as water additives in dose 0.8g/L daily, and G IV: supplied with a combination of magnetic water and yeast in dose 0.8 g/L daily. Our findings revealed that body weight and weight gain did not differ significantly among different groups. The magnetic and yeast groups had significantly lower feed intake and feed conversion ratios, while the combination group had no obvious variation in feed intake matched to the control one. The RBCs count, Hb, PCV, MCV, MCH, and MCHC levels did not differ significantly among different groups. The WBCs count increased significantly in the magnetic water and yeast groups, however, there was no marked difference in the combination group. ALT reduced significantly in magnetic water, whereas AST did not change significantly in any of the groups. Total proteins, albumin, globulin, glucose, uric acid, and creatinine levels did not differ significantly across all groups. Malondialdehyde and GSH showed no statistically significant difference in magnetic water, yeast group, or combination group. IL6 levels increased significantly in the magnetic water and yeast groups, but not in the combination group. IL10 concentrations were markedly lower in the magnetic water and yeast groups, but not in the combination group. It is possible to conclude that using magnetic water and yeast improved growth performance while having no toxic effect in broiler chicken.