A well-produced performance will ensure that an organization runs smoothly. This study investigates the performance of academic personnel. The performance that will be produced is also very dependent on the leadership, ability to use technology and work environment and the work performance of the employees. So that the existence of those factors makes lecturers' performance better and more precise, will be able to make the organization better. This study aims to analyze the effect of different leadership styles, ability to use technology and work environment on lecturer performance with job satisfaction as mediation at universities in Egypt. The approach used in this research is quantitative. The population in this study were academic staff in different universities in Egypt, with a sample size of 360 respondents. The loading, cronbach's α, rho-a and AVE are used to examin the constructs. All Cronbach's alpha values are more than 0.7 and factor loading is more than 0.50. Correlation, regression analysis and structural equation modeling was employed to test research hypotheses. This study finds that transformational leadership style tends to motivate to work better which has a great impact on overall performance. In addition, it suggests that improving the work environment and work environment can significantly increase job satisfaction and performance outcomes at universities in Egypt