Aim: This study was performed to evaluate clinically and radiographically the effect
of nano calcium sulphate bone graft in treatment of intra-bony defects in periodontitis
patients Subjects and Methods: Twenty patients were selected from those attending at
the Outpatient clinic, Oral Medicine and Periodontology Department, Faculty of Dental
Medicine, Al-Azhar University (Assiut Branch) diagnosed as periodontitis cases having
intra bony defect with probing depth > 6 mm and clinical attachment loss ≥ 5 mm. They
were divided into two groups. Group I: included 10 periodontitis patients with intra
bony defects were received open flap surgery combined with nano calcium sulphate
bone graft. Group II: included 10 periodontitis patients with intra bony defects were
received open flap debridement alone. Results: Both groups showed high statistically
significant differences between baseline and 6 months in all clinical parameters
(PI,GI,CAL,PD) and radiographic parameter (bone density BD). There was statistically
significant difference in group I when compared to group II in (CAL,PD,BD) at 6 and
12 months. Conclusion: Using nano calcium sulphate bone graft in treatment of intrabony
defects is effective in treatment of intra-bony defects in periodontitis patients and
it is better than open flap debridement alone.