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375148

The Effect of Liver Transplantation Surgery on Anaerobic Gut Microbiota Community and Vitamin B12 levels

Article

Last updated: 24 Dec 2024

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Subjects

-

Tags

Biology and pharmaceutical sciences.

Abstract

The Anaerobic Gut Microbiota (AGM) is completely associated with human physiology. Compounds like Vitamins, Short Chain Fatty Acids (SCFAs), bile acids, choline metabolites, indole derivatives, polyamines, lipids, neurotransmitters, and neuroactive compounds were linked by the AGM. This study involved 28 Liver transplant (LT) patients from Gastrointestinal Surgery Center (GEC), Faculty of medicine Mansoura University. One hundred and twelve stool and blood samples were taken from all LT patients in the first week before and after the surgery. The results showed that the percentage of anaerobic bacteria isolated from patients before and after one week liver transplantation was (67.18% and 32.82%), respectively. On the other hand, the levels of vitamin B12 (VB-12) in the blood decreased simultaneously with the change of AGM in the first week after surgery compared to the first week before surgery, and this affected the levels of VB12 in the blood of patients with p-value of 0.001.

DOI

10.21608/ajbas.2024.295010.1215

Keywords

Liver transplantation, Anaerobic Gut Microbiota, Vitamin B12

Authors

First Name

mohamed

Last Name

abdel-raouf

MiddleName

Abdel-Raouf

Affiliation

Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

dr.mohamed@mans.edu.eg

City

mansoura

Orcid

-

First Name

Mohamed

Last Name

Abdel-Wahhab

MiddleName

-

Affiliation

Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

wahab_m_eg@yahoo.com

City

Mansoura

Orcid

-

First Name

Ahmed

Last Name

Ismail

MiddleName

-

Affiliation

Faculty of Science, Port Said University, Port Said, Egypt

Email

h.meda77@yahoo.com

City

Port Said

Orcid

-

First Name

Mohsen

Last Name

Ibrahim

MiddleName

El-Sayd

Affiliation

Faculty of Science, Port Said University, Port Said, Egypt

Email

m.elmekawy@gmail.com

City

-

Orcid

-

First Name

Taher

Last Name

Elsheikh

MiddleName

Abozeid

Affiliation

Faculty of Science, Port Said University, Port Said, Egypt

Email

elshiekh0000@gmail.com

City

-

Orcid

0009-0009-3864-5668

First Name

Hisham

Last Name

Aldeweik

MiddleName

Mohammad

Affiliation

Director of Microbiology Lab., Environmental Monitoring Administration, Ministry of Health, Mansoura, Egypt.

Email

hishamdw@gmail.com

City

Mansoura

Orcid

-

Volume

5

Article Issue

4

Related Issue

50702

Issue Date

2024-10-01

Receive Date

2024-06-03

Publish Date

2024-10-01

Page Start

445

Page End

454

Online ISSN

2682-275X

Article File

AJBAS_Volume 5_Issue 4_Pages 445-454.pdf

PDF . 1.6MB

Link

https://ajbas.journals.ekb.eg/article_375148.html

Detail API

https://ajbas.journals.ekb.eg/service?article_code=375148

Order

1

Type

Original Article

Type Code

947

Publication Type

Journal

Publication Title

Alfarama Journal of Basic & Applied Sciences

Publication Link

https://ajbas.journals.ekb.eg/

MainTitle

The Effect of Liver Transplantation Surgery on Anaerobic Gut Microbiota Community and Vitamin B12 levels

Details

Type

Article

Created At

24 Dec 2024