The Egyptian flora has been suffering from great changes in the distribution of some plants since the last flora of Egypt in 2005. The factors affecting this distribution are temperature, rainfall, agricultural practices, construction activities etc. So, the geographical distributions of many species needed to be revised and updated. This investigation updated the distribution of twenty-eight species in different phytogeographical regions of Egypt according to some previous studies and herbarium records. These species were freshly collected materials from different phytogeographical areas. They belonged to fourteen families including twenty-four genera and eight sub-species. The revision of their geographical distribution showed the newly addition of sixteen species to the flora of the Eastern desert. Additionally, eight species were recorded to the flora of Deserts except that of Sinai. Finally, nine species were added to the flora of the Mediterranean region. The present research aims to update the distribution of twenty-eight species in different phytogeographical regions of Egypt according to some previous studies and herbarium records. These species belonged to fourteen families including twenty-four genera and eight sub-species. The revision of their geographical distribution showed the newly addition of sixteen species to the flora of the Eastern desert such as: Cynanchum acutum, Amaranthus blitum and Euphorbia helioscopia. Additionally, eight species were recorded to the flora of Deserts except that of Sinai among them: Heliotropium aegyptiacum, Chloris virgata and Commelina bengnalensis. Finally, nine species were added to the flora of the Mediterranean region e.g., Veronica anagaIlis-aquatica, Leptochola panicea and Chenopodium ficifolium.