Objectives: to identify prevalence, severity, and risk factors of intestinal schistosomiasis in Al-Shmaytin& Al-Mwaset districts-Taiz governorate's-Yemen. Methods: A cross-sectional study using structured questionnaires to collect data: age, gender, marital status, education, income, location, occupation, behavioral features, duration of contact with water, clinical background, schistosomiasis awareness, and the results of stool investigation. SPSS version 24 was used for statistical analysis. Results: S. mansoni prevalence was (14.3%), with a higher prevalence in Al-Mwaset 22.0% compared to Al-Shmaytin 6.9%. Most infections were of high intensity (43.3%). The overall geometric mean egg count was 241.5 EPG. AOR for: district 2.7 (95% CI: 0.94– 7.59), (p=0.000); marital 0.4 (95% CI: 0.15–0.96), (p=0.041); receiving Praziquantel® 0.7 (95% CI: 0.28–1.63), (p=0.218); having dam near home 1.2 (95% CI: 0.43–3.55), (p=0.69); age 0.2 (95% CI: 0.09–0.61), (P= 0.003); having pools/ponds near home 4.2 (95% CI: 0.99–17.90), (p=0.05); defecate near water sources 2.6 (95% CI: 1.09– 6.33), (p=0.003), blood in stool 4.7 (95% CI: 0.08– 0.59), (p=0.004). Conclusions: The residents in the study areas were at moderate risk of developing intestinal schistosomiasis. The infection was more prevalent in Al-Mwaset, ages 6-18, single, living near pools/ponds or dams, defecating near water sources (has the main role), having blood with stool, and didn't receive Praziquantel®. The heavy intensity of infection was noted among most of the infected community, male, aged more than 18 years. It was recommended that Praziquantel® be regularly given to communities