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326102

MRI ASSESSMENT OF CSF FLOW AND DIAGNOSIS OF NORMAL PRESSURE HYDROCEPHALUS

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Last updated: 04 Jan 2025

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Abstract

Background: Normal-pressure Hydrocephalus is a clinical triad of gait disturbance, subcortical dementia, and urinary incontinence in a patient who has communicating hydrocephalus.
Objective: To reveal the role of phase-contrast MR imaging in the detection of normal pressure hydrocephalus among patients with ventriculomegaly.
Patient and Methods: The study group included 40 patients with ventriculomegaly. Patients were referred to the multiple MRI centers (including Nile Scan Radiology Center and Watani Scan Radiology Center), Radiology Department of AL Mokatam Hospital. The consensus about final diagnosis in the ventriculomegaly group was reached on the light of the typical clinical findings and typical conventional MRI findings. The study was done between January 2018 and June 2020. The study was performed on 1.5 Tesla imager, using pulse -gated, cine-phase-contrast MRI technique and CSF quantification software.
Results: This study revealed that the surest phase contrast MRI parameters in predicting normal pressure hydrocephalus was a CSF aqueductal stroke volume greater than 42 μL having a positive predictive value100%.
Conclusion: The study yielded considerable information on the physiology of the normal CSF circulation, and in the evaluation of pathological CSF flow dynamics in normal pressure hydrocephalus that provided a better method of selecting those patients with hydrocephalus who gain benefit most from shunt operation.

DOI

10.21608/amj.2023.326102

Keywords

Normal pressure hydrocephalus, cine phase contrast, ventriculomegally, Atrophy

Authors

First Name

Mosab

Last Name

El-Khair Abdul-Azeem Ghaitah

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Affiliation

Department of Radiodiagnosis, Faculty of Medicine, Al-Azhar University, Cairo

Email

mosabghaita89@gmail.com

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First Name

Abdul-Nabi

Last Name

Byoumi Mohammed

MiddleName

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Affiliation

Department of Radiodiagnosis, Faculty of Medicine, Al-Azhar University, Cairo

Email

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City

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Orcid

-

First Name

Mahmoud

Last Name

Ibrahim El-Shamy

MiddleName

-

Affiliation

Department of Radiodiagnosis, Faculty of Medicine, Al-Azhar University, Cairo

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Volume

52

Article Issue

4

Related Issue

44346

Issue Date

2023-10-01

Receive Date

2023-11-14

Publish Date

2023-10-01

Page Start

967

Page End

978

Print ISSN

1110-0400

Link

https://amj.journals.ekb.eg/article_326102.html

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https://amj.journals.ekb.eg/service?article_code=326102

Order

326,102

Type

Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

Publication Link

https://amj.journals.ekb.eg/

MainTitle

MRI ASSESSMENT OF CSF FLOW AND DIAGNOSIS OF NORMAL PRESSURE HYDROCEPHALUS

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Article

Created At

24 Dec 2024