Background: Introduction of coronary stents in the field of interventional cardiology has significantly improved short- and long-term results of the percutaneous coronary interventions but in the same time they became responsible for development of a new entity called neo-intimal hyperplasia (NIH). If overexpressed, NIH can lead to so-called in-stent restenosis (ISR). The CHA2DS2-VASc score has recently been used to predict not only thromboembolic risk in atrtial fibrillation (AF) but also adverse events in various cardiovascular diseases.
Objective: Assessment of the predictive value of the CHA2DS2-VASc Score in detecting in-stent restenosis among patients who underwent previous revascularization in proximal left anterior descending (LAD) Artery using drug eluting stents (DES) due to stable angina and acute coronary syndrome.
Patients and Methods: This study was a retrospective observational study conducted over 113 patients with previous history of percutaneous intervention (PCI) to Proximal LAD by DES who presented at our cardiology department catheterization laboratory for coronary angiography due to stable angina or acute coronary syndrome .Angiographic ISR was defined as narrowing ≥50% in the stented coronary artery segment.
Results: From total of 113 patients, 38 patients (33.6%) had ISR with CHA2DS2-VASc score equal to or more than 3, (p value =0.033) in ISR group. Also there was a significant relationship between times since PCI of more than 3 years, stent length more than 32 mm and ISR (p value 0.028).
Conclusion: CHA2DS2-VASc score can be used as a simple and effective tool to predict ISR in patients underwent DES implantation in proximal LAD.