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345566

Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts

Article

Last updated: 24 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Clinical Research (Medical)

Abstract

Background:Anogenital warts treatment has always been a demanding entity.  Although several therapeutic options exist, no single modality is completely effective in its treatment rather than preventing recurrence. Aim: To assess the effectiveness ofmicroneedling-assisted topical bleomycin versus cryotherapy in the treatment of anogenital warts. Methods:This trial involved 36 patientswho were split into two groups. Group (A): bleomycin (n=18). Group (B): cryotherapy (n=18). In group (A), microneedling was performed on the lesion followed by spraying of bleomycin (1 U/mL) every two weeks for a total of four sessions. In group (B), Cryotherapy was employed at a two-week interval for a maximum of 4 sessions. Results:By the end of sessions, 15(83.3%) patients in the bleomycin group and 11(61.1%) patients in the cryotherapy group showed complete response of all the warts with a statistically significant difference (P = 0.039).Also, the percentage of improvement was significantly higher in warts with lower duration among both groups. After 6 months, Recurrence was reported only in two (13.3%) patients in the bleomycin group compared to five (45.5%) in the cryotherapy group with a statistically insignificant difference (p=0.095). Conclusion: In treating anogenital warts, microneedling-assisted topical bleomycin is more effective than cryotherapy.
 

DOI

10.21608/scumj.2024.345566

Keywords

Anogenital warts, Bleomycin, Cryotherapy, Microneedling

Authors

First Name

Halim M.

Last Name

Halim

MiddleName

-

Affiliation

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Suez Canal University, Egypt.

Email

halimmaher165@gmail.com

City

Ismailia

Orcid

0000-0003-4310-1576

First Name

Mohammed EM.

Last Name

Gad

MiddleName

-

Affiliation

Dikirnis General Hospital, Mansoura, Egypt.

Email

-

City

-

Orcid

-

First Name

Hesham A.

Last Name

Nada

MiddleName

-

Affiliation

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

First Name

Mohamed AM.

Last Name

Ali

MiddleName

-

Affiliation

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

Volume

27

Article Issue

2

Related Issue

46317

Issue Date

2024-02-01

Receive Date

2024-03-13

Publish Date

2024-02-01

Print ISSN

1110-6999

Online ISSN

2090-2581

Link

https://scumj.journals.ekb.eg/article_345566.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=345566

Order

6

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts

Details

Type

Article

Created At

24 Dec 2024