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323932

Assessment of Quality of Life of Hepatitis C Virus Patients after Treatment with Direct-Acting Antiviral Drugs

Article

Last updated: 24 Dec 2024

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Tags

Clinical Research (Medical)

Abstract

Background: Infection with the hepatitis C virus (HCV) is one of the major causes of liver disease around the world. There is some disagreement as to the prognosis of patients with chronic hepatitis C. Most patients with chronic hepatitis C will have a normal life span and not suffer the consequences of this disease. Health-Related Quality of Life (HRQoL) has gained prominence as a tool to assess the impact of chronic diseases and their treatments on the perception of health and patient well-being. Aim: To improve health-related quality of life among Egyptian hepatitis C virus patients.Patients and Methods: A cross-sectional study was conducted on 80 patients who received direct-acting antiviral agents at the Center of Treatment of Viral Hepatitis in Ismailia Fever Hospital. The statistical analyses were performed according to onset age, the presence of family history, clinical examination, and severity of the disease. Results: This study showed the mean score of questionnaires as regards abdominal symptoms was 2.72 in studied patients, fatigue was 3.04, systemic symptoms were 3.20, activity was 3.5, emotional functions were 3.59 and worry was 3.90. Conclusion: patients with chronic hepatitis C with or without cirrhosis have markedly reduced HRQOL. Patients who had a sustained response (virological or biochemical) to interferon therapy experienced significant improvements in perceived wellness and functional status. Successful interferon therapy provides meaningful improvements in HRQOL in patients with chronic hepatitis C.
 
 

DOI

10.21608/scumj.2023.323932

Keywords

Hepatocellular carcinoma, Chronic liver disease

Authors

First Name

Hani A.

Last Name

El sayed

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Mansoura University, Egypt.

Email

hanyahmed1012@gmail.com

City

-

Orcid

-

First Name

Khalil A.

Last Name

Khalil

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine-Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

First Name

Ashraf M.

Last Name

El-Tantawy

MiddleName

-

Affiliation

Department of Psychiatry, Faculty of Medicine, Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

First Name

Nashaat M.

Last Name

Soliman

MiddleName

-

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

Volume

26

Article Issue

9

Related Issue

44148

Issue Date

2023-09-01

Receive Date

2023-10-30

Publish Date

2023-09-01

Page Start

29

Page End

39

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 26_Issue 9_Pages 29-39.pdf

PDF . 330.0kB

Link

https://scumj.journals.ekb.eg/article_323932.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=323932

Order

4

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Assessment of Quality of Life of Hepatitis C Virus Patients after Treatment with Direct-Acting Antiviral Drugs

Details

Type

Article

Created At

24 Dec 2024