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323930

Effect of Long-Term Soft Contact Lens Wearing on Corneal Endothelial Cells and Central Corneal Thickness

Article

Last updated: 24 Dec 2024

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Clinical Research (Medical)

Abstract

Background: Long-term use of contact lenses may lead to various changes in the tear layer, conjunctiva, and cornea depending on the oxygen-permeability of lenses. Contact lens-induced- hypoxia and corneal edema caused by acidosis. Aim: to evaluate the effect of long-term, soft contact lens wear on corneal endothelium and corneal thickness aiming at improving the quality of vision in contact lens wearers and keeping their corneas healthy as considered a precious refractive surface of the eye. Patients and Methods: This cross-sectional case-control study included 96 eyes (48 right and 48 left eyes) of 48 participants randomly selected with the age group between 18-30 years, 30 female, and 18 male. Participants were divided into two groups (case and control group) each of which included 48 eyes. Results: There is a statistically significant difference between both groups regarding BCVA (p < /em>= 0.001). while, the changes in CCT in contact lens wearers were not statistically significant (p < /em> =0.9) unlike the morphological parameters as CD (P <0.001), CV (p- =0.004), SD (p- =0.001) which shows statistically significant changes. There was no significant difference as regards (CCT), the hexagonal appearance of the cell (HEX%), and average cell area (AVG) between the contact lens wearer and control group. The baseline means of endothelial cell density in group 1 was 2911 ± 244 cells/mm2, while group 2 was 2610 ± 173 cells/mm2. There was a statistically significant difference between the case and control group as regards endothelial cell density (ECD) (p < /em> <0.001). The mean of (CV%) in group 1 was (28 ± 6), while in group 2 was (28 ± 6). There was a statistically significant difference between the contact lens wearer and the control group as regards (CV%) (p < /em> = 0.004). Conclusion: Long-term soft contact lens use (> 1 year) affects cell density (CD) and morphological features (coefficient of variation (CV), pleomorphism, and polymegathism).

DOI

10.21608/scumj.2023.323930

Keywords

Soft contact lens, Corneal Endothelial Cells, Central Corneal Thickness

Authors

First Name

Esraa

Last Name

Mansour

MiddleName

-

Affiliation

Department of Ophthalmology, Port Said Ophthalmology Hospital, Port Said, Egypt.

Email

esraa.zakaria@med.suez.edu.eg

City

portsaid

Orcid

-

First Name

Mervat E.

Last Name

Elgharieb

MiddleName

-

Affiliation

Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

Email

-

City

-

Orcid

-

First Name

Ehab M.

Last Name

Moawad

MiddleName

-

Affiliation

Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

Email

-

City

-

Orcid

-

Volume

26

Article Issue

9

Related Issue

44148

Issue Date

2023-09-01

Receive Date

2023-10-30

Publish Date

2023-09-01

Page Start

21

Page End

28

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 26_Issue 9_Pages 21-28.pdf

PDF . 322.5kB

Link

https://scumj.journals.ekb.eg/article_323930.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=323930

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3

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Effect of Long-Term Soft Contact Lens Wearing on Corneal Endothelial Cells and Central Corneal Thickness

Details

Type

Article

Created At

24 Dec 2024