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357513

Efficiency of Platelet-Rich Plasma in Repairing Tympanic Membrane Perforation

Article

Last updated: 24 Dec 2024

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Clinical Research (Surgical)

Abstract

Background: Myringoplasty is the definite treatment of tympanic membrane perforation. Aim: This study aimed to assess the success rate in repairing tympanic membrane perforation of Platelet platelet-rich plasma myringoplasty method. Patients and Methods: In our study, we have 27 TM perforations in 24 patients (where 3 patients had bilateral perforation) with small and medium-sized tympanic membrane perforations. We excluded subtotal or marginal perforation. In our study, Myringoplasty involves the repair of tympanic membrane perforation with a Platelet-rich plasma graft. Platelet-rich plasma graft was used as an overlay graft through the EAC under local anesthesia to act as a support for the Tympanic membrane to grow on both sides of the Platelet-rich plasma graft and enhance the success rate through its growth factors. Results: Graft uptake and complete closure of tympanic membrane were observed in 87.5% of cases (85.2% in relation to a number of perforations), Small-sized TM perforation documented 93.3% success rate (14 perforations of 15), while medium-sized TM perforation documented 75% success rate (9 perforations of 12). Platelet-rich plasma graft provides a better audiological result, hearing gain by >10 dB was achieved in 87.5% of patients. Conclusion: Platelet-rich plasma is a highly successful auto graft for closure of small tympanic perforations, fairly successful in medium-sized perforation, and provides unlimited graft material for residual perforations after failure fascia graft.
 

Keywords

PRP, Myringoplasty, tympanic membrane perforation

Authors

First Name

Ahmed M.

Last Name

Abdelazez farag

MiddleName

-

Affiliation

Department of Otorhinolaryngology, Military Production Hospital.

Email

dr.a7medsallam.sur@gmail.com

City

-

Orcid

-

First Name

Nagy M.

Last Name

Eskander

MiddleName

-

Affiliation

Department of Otorhinolaryngology, Faculty of Medicine-Suez Canal University

Email

-

City

-

Orcid

-

First Name

Yasser T.

Last Name

Madian

MiddleName

-

Affiliation

Department of Otorhinolaryngology, Faculty of Medicine-Suez Canal University

Email

-

City

-

Orcid

-

First Name

Yehia M.

Last Name

Ashry

MiddleName

-

Affiliation

Department of Otorhinolaryngology, Faculty of Medicine-Suez Canal University

Email

-

City

-

Orcid

-

Volume

26

Article Issue

10

Related Issue

43656

Issue Date

2023-10-01

Receive Date

2024-06-01

Publish Date

2023-10-01

Page Start

35

Page End

44

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 26_Issue 10_Pages 35-44.pdf

PDF . 443.8kB

Link

https://scumj.journals.ekb.eg/article_357513.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=357513

Order

5

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Efficiency of Platelet-Rich Plasma in Repairing Tympanic Membrane Perforation

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Article

Created At

24 Dec 2024