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329175

Maternal Serum Vitamin D Level in Preeclampsia Versus Normotensive Pregnant Females: A Comparative Study

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Last updated: 04 Jan 2025

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Clinical Research (Medical)

Abstract

Background: Preeclampsia is a severe medical disorder affecting pregnant women. Vitamin D was thought to play an essential role in its pathogenesis. Aim: To evaluate the association between vitamin D and preeclampsia. Materials and Methods: This case-control study was conducted at the obstetrics and gynecology department at Suez Canal University Hospital. We recruited patients admitted to the ward diagnosed with mild or severe preeclampsia and another group of normotensive women as a control one. They were subjected to complete history taking, blood pressure measurement, urine analysis to detect proteinuria using a dipstick screening strip, and vitamin D analysis. Neonatal serum calcium was measured. Results: There was a significant difference in vitamin D levels which was significantly decreased in women with severe PE (p-value < 0.001). Women with severe preeclampsia were delivered by cesarean section than their peers (p-value 0.017). The neonatal total serum calcium level was significantly lower among preeclampsia groups (p=0.003). Also, the birth weight of the neonates was significantly lower among preeclampsia groups (p < 0.001). Conclusion: Vitamin D deficiency affects a significant proportion of pregnant women. Vitamin D deficiency was associated with the occurrence of PE.

DOI

10.21608/scumj.2023.329175

Keywords

Vitamin D, preeclampsia, Neonatal hypocalcemia

Authors

First Name

Nashwa Y.

Last Name

Hassan

MiddleName

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Affiliation

Port Said Specialized Obstetrics and Gynecology Hospital, Port Said, Egypt

Email

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City

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Orcid

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First Name

Mohamed A.

Last Name

El-Bahey

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University, Egypt

Email

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City

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Orcid

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First Name

Abeer B.

Last Name

Ahmed

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University, Egypt

Email

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City

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Orcid

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First Name

Ahmed A.

Last Name

Abo Alroos

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University, Egypt

Email

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City

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Orcid

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Volume

26

Article Issue

10

Related Issue

43656

Issue Date

2023-10-01

Receive Date

2023-12-07

Publish Date

2023-10-01

Page Start

18

Page End

25

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 26_Issue 10_Pages 18-25.pdf

PDF . 353.1kB

Link

https://scumj.journals.ekb.eg/article_329175.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=329175

Order

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Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Maternal Serum Vitamin D Level in Preeclampsia Versus Normotensive Pregnant Females: A Comparative Study

Details

Type

Article

Created At

24 Dec 2024