ManageChatDiscover
308797

Evaluation of the Role of Platelet-Rich Fibrin (PRF) in the Management of Mandibular Bony Cysts after Surgical Enucleation

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical Research (Surgical)

Abstract

Background: Cystic mandibular lesions may be epithelial or non-epithelial, odontogenic, or non-odontogenic, developmental, or inflammatory in origin. Clinically bony cysts are usually asymptomatic and are often accidentally discovered on routine radiological examination. PRF has been shown to act as a suitable scaffold for culturing human periosteal cells in vitro, which may be suitable for bone tissue engineering applications. Aim: This study aimed to explore the clinical and radiographic effectiveness of autologous PRF in the treatment of intrabony cyst cavity after enucleation. Subjects and Methods: The present study was designed as a randomized controlled clinical trial that included patients with mandibular bony cysts as well as benign tumors of the mandibular surgery department at Suez Canal University Hospital and Suez Health Insurance Hospital. The study participants were randomly divided into two groups: i) the study group who underwent enucleation of the cysts then PRF was added and ii) the Control group who underwent enucleation of the cysts only. Results: In the control group, the mesiodistal length of the cyst at 6 months after enucleation (2.53 ± 1.74) was significantly lower than that length just after operation (3.03 ± 1.93) (p < 0.001). However, there was no statistically significant difference in mesiodistal length of the cyst just after the operation (3.03 ± 1.93) and 2 months after enucleation (2.98 ± 1.96). Meanwhile, in the PRF group, the mesiodistal length of the cyst just after the operation (3.17 ± 1.89) was significantly lower than that length at 2 and 6 months after enucleation (2.20 ± 1.35) and (1.43 ± 1.44) (p < 0.001).Patients who received PRF had significantly lower 6 months from baseline change in each mesiodistal length (p=0.001) and superior-inferior length (p=0.002) than patients in the control group. Conclusion: PRF promotes faster osseous regeneration in the Management of mandibular bony Cysts after Surgical Enucleation. The use of PRF in the management of cystic lesions seems to be a novel therapeutic approach promoting faster osseous regeneration.
 

DOI

10.21608/scumj.2023.308797

Keywords

Platelet-Rich Fibrin (PRF), Mandibular Bony Cysts, Surgical Enucleation

Authors

First Name

Amr A.

Last Name

Gomaa

MiddleName

-

Affiliation

Department of Plastic Surgery, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

El said

MiddleName

-

Affiliation

Department of Plastic Surgery, Faculty of Medicine, Suez Canal University, Egypt

Email

ahmedalaapriv@gmail.com

City

Suez

Orcid

-

First Name

Mohamed A.

Last Name

El Badawy

MiddleName

-

Affiliation

Department of Plastic Surgery, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmad E.

Last Name

Mohamed

MiddleName

-

Affiliation

Department of Plastic Surgery, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

Volume

26

Article Issue

6

Related Issue

42520

Issue Date

2023-06-01

Receive Date

2023-07-18

Publish Date

2023-06-01

Page Start

1

Page End

8

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 26_Issue 6_Pages 1-8.pdf

PDF . 267.4kB

Link

https://scumj.journals.ekb.eg/article_308797.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=308797

Order

1

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Evaluation of the Role of Platelet-Rich Fibrin (PRF) in the Management of Mandibular Bony Cysts after Surgical Enucleation

Details

Type

Article

Created At

24 Dec 2024