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308214

Predictors of Central Sensitization and Pain Quantification in Patients with Carpal Tunnel Syndrome

Article

Last updated: 04 Jan 2025

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Tags

Clinical Research (Medical)

Abstract

Background: Carpal tunnel syndrome (CTS) occurs following compression of the median nerve within the carpal tunnel leading to paresthesia and pain in the median nerve distribution, numbness, and falling of objects out of the patient's hand. It affects 2.7% of the general population. The prevalence of CTS in Upper Egypt and the other types of peripheral neuropathies is about 1686/100,000 with a female-to-male ratio of 10 /1. Aim: to evaluate the predictors of central sensitization and pain quantification in patients with unilateral, mild to moderate CTS. Methods: This study was conducted on 84 patients recruited at the electrodiagnosis Clinic at the Suez Canal University Hospital after fulfilling the eligibility criteria. Patients were evaluated by history, clinical examination, nerve conduction studies, and outcome measures by VAS for pain, Boston carpal tunnel questionnaire, central sensitization inventory, sensory threshold, pain threshold, and pressure pain threshold. Results: In this study, pain was evaluated by VAS score which was 9 ±1.23. Results for the symptoms severity scale were evaluated by the Boston CTS questionnaire which was 3.92 ± 0.83. The functional status scale was 3.75 ± 1.08. Central sensitization inventory (CSI) was 50.83 ±10.57. Regarding sensory and pain thresholds for electrical stimulation, there were significantly lower sensory and pain thresholds in CTS patients in comparison to healthy subjects. Concerning pressure pain threshold, patients with CTS had lower thresholds over the median, ulnar, radial, and C5-6 zygapophyseal joints compared to healthy individuals. Conclusion: CTS can be associated with central sensitization which is manifested by augmented response to pain.  

DOI

10.21608/scumj.2023.308214

Keywords

Carpal tunnel syndrome, Central Sensitization, Pain Sensitization

Authors

First Name

Gehad

Last Name

Swilam

MiddleName

-

Affiliation

Physical Medicine, Rheumatology and Rehabilitation Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

gehad_swilam@med.suez.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Maaty

MiddleName

-

Affiliation

Physical Medicine, Rheumatology and Rehabilitation Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

aimaaty@hotmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Fouad

MiddleName

-

Affiliation

Occupational Medicine Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

fouad.oemed@gmail.com

City

-

Orcid

-

First Name

Ali

Last Name

Elsayed

MiddleName

-

Affiliation

Physical Medicine, Rheumatology and Rehabilitation Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

ali_elsayed@med.suez.edu.eg

City

-

Orcid

-

First Name

Mona S.

Last Name

Ghaly

MiddleName

-

Affiliation

Physical Medicine, Rheumatology and Rehabilitation Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

Volume

26

Article Issue

5

Related Issue

42291

Issue Date

2023-05-01

Receive Date

2023-07-17

Publish Date

2023-05-01

Print ISSN

1110-6999

Online ISSN

2090-2581

Link

https://scumj.journals.ekb.eg/article_308214.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=308214

Order

10

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Predictors of Central Sensitization and Pain Quantification in Patients with Carpal Tunnel Syndrome

Details

Type

Article

Created At

24 Dec 2024