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304958

Drug Repurposing in Primary Healthcare: A review

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical Research (Medical)

Abstract

The process of finding new medical indications for old drugs is known as drug repurposing or repositioning. As opposed to de novo drug discovery, drug repurposing strategies may be less costly, less time-consuming, and relatively safer. This process may be explained by common molecular pathways that contribute to many different diseases. Additionally, adverse effects of certain drugs may provide desirable effects in other disease states. The drug approval process may differ from one indication to another and between countries. Based on clinical trials and physicians' experiences, the use of off-label prescriptions is a common practice in medicine. Primary healthcare providers are gatekeepers for an efficient healthcare system as they face many challenges in managing patients with multiple comorbidity and polypharmacy. Repurposing certain drugs may be helpful to tackle these challenges. This review outlines the current most promising medications with potential multiple indications and their supporting evidence in primary healthcare.
 

DOI

10.21608/scumj.2023.304958

Keywords

Multiple indications, primary health care, Repositioning, repurposing, off-label

Authors

First Name

Wael

Last Name

Zeid

MiddleName

-

Affiliation

Department of Family Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

waelzeid@yahoo.com

City

-

Orcid

-

Volume

26

Article Issue

3

Related Issue

41996

Issue Date

2023-03-01

Receive Date

2023-06-24

Publish Date

2023-03-01

Page Start

1

Page End

8

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 26_Issue 3_Pages 1-8.pdf

PDF . 213.3kB

Link

https://scumj.journals.ekb.eg/article_304958.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=304958

Order

1

Type

Review Article

Type Code

2,902

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Drug Repurposing in Primary Healthcare: A review

Details

Type

Article

Created At

24 Dec 2024