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287284

Evaluation of Sentinel Lymph Node Mapping in Uterine Cancer Staging

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Clinical Research (Surgical)

Abstract

Background: Lymphatic mapping recently emerged as a promising new strategy and is increasingly being adopted by gynecologic oncology practices worldwide. The sentinel lymph node is a technique used to properly detect nodal metastases hence improving staging accuracy with the subsequent proper application of adjuvant therapy. Aim: to evaluate of the accuracy of sentinel lymph node biopsy using a patant blue dye in endometrial and cervical malignancies. Patients and Methods: Twenty-six patients, diagnosed with endometrial cancers stage (I/II) by MRI, and three patients, diagnosed with cervical cancers stage (Ia/IIa) by MRI, were enrolled in the study. Results: Sentinel lymph node(s) were successfully identified in 18 patients (69.2%) with endometrial carcinoma and one case with cancer cervix. The sensitivity of sentinel Lymph node mapping in the detection of lymph node metastasis was 100% with a negative predictive value of 100% and 0% false negative rate. There was a statistically significant inverse relation between sentinel lymph node detection and tumor grading. There was a statistically significant relation between sentinel lymph node detection and both cervical involvement and positive lymph node metastasis. Conclusion: Sentinel Lymph node mapping in cases of early-stage endometrial cancer is a good option to avoid overtreatment with unnecessary removal of more lymph nodes, which may result in an increase in perioperative adverse effects.
 

DOI

10.21608/scumj.2023.287284

Keywords

sentinel lymph node, Lymphatic Mapping, Endometrial carcinoma, Cancer cervix

Authors

First Name

Hamada

Last Name

Fathy

MiddleName

-

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

dr.hamada@med.suez.edu.eg

City

-

Orcid

-

First Name

Mahmoud

Last Name

Hussin

MiddleName

-

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

mgmhussin@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

AboBakr

MiddleName

-

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Solimam

Last Name

El-Kammash

MiddleName

-

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Gomaa

MiddleName

M.

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

Volume

26

Article Issue

1

Related Issue

39420

Issue Date

2023-01-01

Receive Date

2023-02-25

Publish Date

2023-01-01

Page Start

70

Page End

75

Print ISSN

1110-6999

Online ISSN

2090-2581

Link

https://scumj.journals.ekb.eg/article_287284.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=287284

Order

8

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Evaluation of Sentinel Lymph Node Mapping in Uterine Cancer Staging

Details

Type

Article

Created At

24 Dec 2024