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Role of Exercise Stress Echocardiography in the Detection of Subclinical Diastolic Dysfunction in Asymptomatic Diabetics

Article

Last updated: 04 Jan 2025

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Tags

Clinical Research (Medical)

Abstract

Background:Subclinical left ventricular dysfunction is not uncommon and is a predictor of heart failure. Diabetes commonly presents with exertional dyspnea and reduced exercise tolerance, which is due to diastolic dysfunction. Diastolic exercise echocardiography is a relatively novel modality to detect latent diastolic dysfunction. Aim: We aimed to evaluate the different parameters that affect raised filling pressure during exercise in asymptomatic diabetics using exercise stress echocardiography. Subjects and Methods:This is a case-control study that included 70 persons (35 diabetics and 35 normal volunteers age and sex-matched) who had exertional dyspnea but were asymptomatic at rest. They had a normal systolic and diastolic functions at rest. They did treadmill exercise stress ECG. Post-peak stress images were obtained as quickly as possible after the patient transferred from the treadmill to the imaging table measuring the E/e' ratio. Results:Filling pressure raised dramatically in the diabetic group compared to non-diabetics. Using linear regression analysis, HbA1c as a continuous variable, duration of DM, and waist circumference showed a positive linear significant association with E/e' during exercise. Conclusion:HbA1c level, duration of DM, waist circumference, and eGFR are related to subclinical diastolic dysfunction in asymptomatic diabetics during exercise.  

DOI

10.21608/scumj.2023.284000

Keywords

Diastolic Dysfunction, Heart failure, Stress Echocardiography

Authors

First Name

Ahmed

Last Name

Fareed

MiddleName

M.

Affiliation

Cardiology Department, Faculty of Medicine, Suez Canal University, Egypt

Email

amfareed@yahoo.com

City

-

Orcid

-

First Name

Fathy

Last Name

Nada

MiddleName

A.

Affiliation

Cardiology Department, Faculty of Medicine, Suez Canal University, Egypt

Email

fathynada45@hotmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Elhawary

MiddleName

A.

Affiliation

Cardiology Department, Faculty of Medicine, Suez Canal University, Egypt

Email

hawary51@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Oraby

MiddleName

A.

Affiliation

Cardiology Department, Faculty of Medicine, Suez Canal University, Egypt

Email

maoraby@yahoo.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Abodelmonem

MiddleName

H.

Affiliation

Cardiology Department, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

Volume

26

Article Issue

1

Related Issue

39420

Issue Date

2023-01-01

Receive Date

2023-02-03

Publish Date

2023-01-01

Page Start

40

Page End

46

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 26_Issue 1_Pages 40-46.pdf

PDF . 476.0kB

Link

https://scumj.journals.ekb.eg/article_284000.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=284000

Order

4

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Role of Exercise Stress Echocardiography in the Detection of Subclinical Diastolic Dysfunction in Asymptomatic Diabetics

Details

Type

Article

Created At

24 Dec 2024