Although there are multiple environmental pollutants, heavy metals such as cadmium (Cd) represent the most serious one because of the oxidative stress they induce. The emerging evidence suggests that herbal medicine has become an essential alternative medical approach due to its natural identity and the lack of deleterious side effects. Many health benefits have been documented to phytochemicals such as flavonoids, polyphenols, alkaloids, and carotenoids, including putative antioxidant impacts thereby alleviating various oxidative stress conditions. Syzygium cumini is a type of plant that is rich in a variety of physiological phytochemical compounds. These compounds were observed to be present in various parts of the plant including leaves, seeds, peel, and pulp. Because of these compounds, the fruit of this plant is claimed to have anti-diabetic, anti-hyperlipidemic, antioxidant, hepatoprotective, antimicrobial, anti-inflammatory, antipyretic, antiplaque, radioprotective, neuropsycho-pharmacological, nephroprotective, and antidiarrheal properties as well as the ability to improve fertility in both male and females. The focus of this review is mainly on the antioxidant effects of Syzygium cumini fruit pulp extract against the reproductive challenges caused by exposure to cadmium.