Heavy metals are considered serious environmental pollutants. Industrialization activity has put high amounts of toxic effluents, containing toxic metals into the environment. Therefore, there is an urgent need for industrial wastewater treatment. This study aims to lead bioremoval by active Pb-resistance bacterial cells. Only five bacterial isolates were obtained from industrial wastewater samples. Isolate NDSL2 withstood lead concentrations, MIC recorded at 180 μg/ml, and selected as the most resistant isolate. By depending on morphological and molecular characterizations, it was identified as Bacillus amyloliquefaciens MPA 1034 strain. The optimized conditions for improving Pb-bioremoval efficiency were established. Maximum bioremoval of lead has been revealed 70% by growing and active bacterial cells after 3 days at pH 7, in the presence of lactose, sodium nitrate and yeast extract. SEM, EDX and FTIR analysis confirmed Pd uptake in and/or bound on bacterial cells. Thus, it could be recommended to use Pb-resistance bacterial strain as bioremoval and remediate polluted industrial effluents.