The present study was carried out to investigate the influence of dietary supplementation with vegetable oil sources and dietary red cranberry powder (RB)on growth performance, carcass yield, blood parameters and gut morphology of broiler chickens. In all, 192 1-day-old Ross 308 broiler chickens were randomly divided into 8 treatment groups, each of which included 3 replicates. A completely randomized block design with a 4×2 factorial arrangement of treatments was used for four different sources of oil (1.5% olive oil (OO), 1.5 % flaxseed oil (FO), 1.5% soybean oil (SO) and 1.5% their mixtures oil (MO) in the diets ) then each treatment sub-divided into two dietary RB (0.0 or 1.0 g RB/kg diet). Supplementation of flaxseed oil at the level of 15 g/kg diet produced a positive effect on the production performance of chicks during the whole experimental period compared to the other different oils. Also adding the RB at level 1 g/kg improved the production performance significantly of broiler chickens during the whole experimental period. On the other hand, significantly lower serum levels of total protein and globulin were found with dietary supplementation of FO for broiler chickens compared with the groups fed OO or SO. The duodenum of birds fed a MO and FO showed greater villus height compared with those fed OO and SO. The present study shows that supplementing with FO of diet and adding RB has a positive effect on productivity, some blood parameters and gut morphology in broiler chickens.