Climate change refers to the long-term alterations in weather, including temperatures and humidity patterns. Such deviations can be natural, due to changes in the sun's motion or large volcanic eruptions, or induced due to the current global epidemics and wars. However, investigation into why change in environmental exposure impacts the mammalian reproductive system has increased dramatically in the previous decades. This is because damage to the reproductive system may result in changes in genes, hereditary cancer, or either temporary or permanent infertility. Sperm quality has been declining over the past years due to several factors, including environmental alterations and pollutions. One of the major problems facing rabbit production is heat stress in hot regions of the world, especially during summer season. Therefore, those responsible for promoting the production process and improving reproduction have come to the idea of artificial insemination for a long time to overcome the problems facing the reproductive and productive processes. They have resorted to looking at the previously mentioned process, through which the safety of the semen used in the process of reproduction and production is examined and verified. The large-scale use of AI in rabbit farming dates back to the late 80s. Artificial insemination involves the collection of semen and examination of sperm quality from a male, usually of superior genetic merit, followed by the transfer of that semen to an asexually receptive female in order to result in fertilization. It has become one of the most important techniques ever devised for the genetic improvement of rabbit's farm. Heat stress adversely affects welfare and semen quality, fertility and economy of production in rabbits farming. Finally, we can recommend that AI in rabbits under climate change become more economic in rabbits farming compared with natural mating.