Background: Nutritional knowledge is important issue because it influences healthy food choices and dietary pattern. Deaf students require specially developed nutrition education materials and programs that can be understood quickly and easily. Aim: The present study aimed to; explore effect of nutrition health education module through design of website channel on nutritional knowledge and practice of deaf students in Mansoura city. Subjects and Method: Design: a quasi-experimental research design with one group pre/post-test approach was used. Setting: the study conducted in Al-Amal school for deaf students in El Mansoura city. Subjects: included a purposive sample of 74 deaf students. Tools: Two tools were used for data collection consisted of; Deaf students' knowledge about healthy nutrition questionnaire, and Deaf Students' Health assessment questionnaire. The Results: 83.8% of the deaf students had poor levels of knowledge pre-intervention, which decreased to 8.1% had poor levels of knowledge post-intervention with statistically significant differences between total deaf students' knowledge levels pre- and post-intervention. 97.3% of the deaf students had poor levels of practice pre-intervention which decreased to only 6.8% had poor levels of practice post-intervention with statistically significant differences between total deaf students' practice levels pre- and post-intervention. Conclusion: the nutritional health education module through design website channel proved an invaluable resource for deaf students, significantly enhancing their knowledge and skills in the field of nutrition. Recommendations: to guarantee the program's efficacy and long-term effects, integrate nutritional health into deaf schools' activities. To ensure the program's efficacy and long-term effects, it is recommended that nutritional health be integrated into the activities of deaf schools.