Background: Compassion and work engagement are essential to healthcare organizations and have a good effect on medical facilities, patients, and healthcare practitioners. To ascertain whether a relationship exists that could be advantageous to the healthcare organization, the possible relationship between work engagement and compassion should be investigated. Aim: To explore the relation between organizational compassion and work engagement among nurses in healthcare organizations. Subjects and Method: The current study used a descriptive correlational research design. 265 out of the 413 nurses employed on Damietta General Hospital and Heartand Digestive System Institute at all units of the hospitals' during the study's duration.. Along with a questionnaire on personal and clinical factors, two measures were used to gather data: the job engagement scale and the organizational compassion scale, in addition to personal and job characteristics questionnaire. Results:The study showed that whereas 1.1% of the nurses tested reported having a low opinion of organizational compassion, more than half (53.6%) of the the studied nurses had a moderate perspective. 60.8% of respondents reported being highly engaged at work, compared to 0.4% who reported being lowly engaged. Additionally, a positive statistically significant difference was discovered between the overall ratings of work engagement and organizational compassion perception. Conclusion: Work engagement and overall organizational compassion perception scores exhibited a statistically significant positive correlation. Recommendations: It is advised that nurses' compassion and level of work involvement be routinely assessed and monitored. Creating a motivating work environment and strengthening the nurses' perception of organizational compassion.