Background:Nurses' work engagement and knowledge sharing reduce negative outcomes for healthcare organizations as well as the quality of their performance outcomes.The aim: to examine the relationship between work engagement and knowledge sharing among nurses at healthcare organizations. Design: A descriptive correlational research design .Setting: at As Salam Hospital that affiliated to the Health Insurance System of the Ministry of Health in Port Said Governorate. Subjects 294 nurses: Tools. Work Engagement Scale and Knowledge Sharing Scale. Results: The study revealed nearly two thirds (63.1%)  of nurses who were studied had a moderate level of work engagement. Also, 3.4% of them had a high level of work engagement. While, more than half (54.6%) of nurses had a fair level of knowledge sharing, Also, (8.2%) of them had high level of knowledge sharing. Conclusion: the highest mean score among studied  nurses' responses regarding emotional engagement domain, while lowest mean score was among studied  nurses' responses regarding behavioral engagement. Regarding studied nurses 'responses related to knowledge sharing domains highest mean scores were related to organizational climate, behavioral control, and reputation enhancement. While the lowest mean score related to organizational climate (Innovation).In addition, knowledge sharing positively and significantly influence work engagement Recommendation: Educational program about knowledge sharing and its impact on work engagement.