Background: The most prevalent kind of urine incontinence in word wide, stress urinary incontinence that has an impact on women quality of life at various phases of their lives. According several previous studies, pelvic floor muscle training program is the best way for rehabilitating and strengthening pelvic floor muscles. Aim: To evaluate the effect of pelvic floor muscle training program on quality of life among women with stress urinary incontinence. Subjects and method: Design: A quasi-experimental design was utilized (one group). Subjects: 110 women who have been diagnosed with stress urine incontinence. Setting: This study was applied in gynecologic outpatient clinics at hospitals and primary health care centers that follow comprehensive health insurance. Tools for data collection: A structured interview, woman's health assessment questionnaire, The Incontinence Impact Questionnaire-Short Form (IIQ) -7, and Follow up assessment sheet. Results: Training program was effective in reducing the severity of urine incontinence in the post- and follow-up periods (5.5% and 6.4%). Mean scores of quality of life were improved at post and follow up phase (18.7±0.3, 18.0±3.1 respectively) after providing training program compared to preprogram phase (8.01±2.9) with highly statistically significant difference (p= .000). Also, mean score of women knowledge were improved at post and follow up phase (12.2± 1.2 and 11.3 ±1.8, respectively). Conclusion: Pelvic floor muscle training program was effective in improving women's quality of life and reduced stress urinary incontinence. Recommendations: Making available manual for ongoing education and training about pelvic floor muscle exercises for all women with stress urinary incontinence.