Background: The postpartum period is described as the most essential, yet underappreciated, phase in the lives of mothers and babies; the majority of maternal and neonatal deaths occur during this time. As a result, improved follow-up care has an impact on maternal self-confidence aimed to evaluate the effect of prenatal educational guidelines on maternal practices and coping. Subjects and method: Design: a quasi-experimental design was used Setting: For selected women at the antenatal care clinics of family health units in Port-Said city, namely the El-Kuwait and Othman Bin Affan units Subjects: After meeting requirements, a total of 160 women were recruited. Three tools The structured interviewing scheduale, Postpartum Women's Practice Questionnaire, and Coping with Motherhood scale were used to collect data first. The Results In both the research and control groups, relatives and friends were the most stated sources of information. Women in the study group had higher practice, problem-focused and emotion-focused coping ratings than women in the control group beginning in the post-intervention period, as well as more sufficient responses in stages 1 and 2 of follow-up, the difference was statistically significant (p 0.005). Conclusions: Educational instructions that were implemented had a positive impact on women's practices and coping mechanisms. Recommendations: To improve their practice and coping, all pregnant women should be advised about postnatal care discharge policies. In addition, more study is being conducted to determine the elements that influence women's involvement in these sessions.