Background: Patients with traumatic fractures require traction or internal fixation, which necessitates the use of skilled nurses to satisfy the patient's demands and avoid complications. As a result, orthopedic nurses play a crucial role in the treatment of patients who require traction or internal fixation., Aim: To evaluate the effect of an educational module on enhancing nurses' knowledge for orthopedic patients with traction or internal fixation. Subjects and method:  Design: A quasi experimental research design was utilized in this study. Setting: The study was carried out at orthopedic department in (Mansoura University Hospital and Mansoura Emergency Hospital). Subjects: A convenient sample of staff nurses (50 nurses) who were working in the previously mentioned settings and participate in this study. Tools: The data were collected using Nurses' Knowledge Questionnaire. Results: The study results indicated that 88% of studied nurses had satisfactory total level of knowledge regarding orthopedic patients with traction or internal fixation immediately post educational module implementation with statistically significant differences whereas (p-value=0,001).Conclusion: Nurses' Knowledge was improved after educational module implementation. Recommendations: Providing continuous inservice training for nurses related to nursing care of orthopedic patients with traction or internal fixation.