Background: Risk management plays a major role in shrinking uncertainties and enhancing rich opportunities for different areas of the health system. Aim: The study aimed to enhance nurses' performance regarding risk management through developing a risk management training strategy at Port Said General Hospital. Design: Quasi-experimental design. Setting: This study was carried out at a selective department in Port Said General Hospital. Subject: included all nurses working at the selected inpatient units in Port Said general Hospital at the study time with a total number of 53 nurses. Tool: two tools were used; first tool: a risk management knowledge questionnaire was used to assess nurses' knowledge second tool: an observational checklist was used to assess nurses' practice Results: Pre-training, nurse's knowledge related to risk management dimensions as a mean percentage was 47.7±20.2, which improved post-training to be 86.5±24.2 During follow up, this percentage declined to be 74.9±40.6. Pre-training, nurse's practice related to risk management dimensions, 32.1% of nurses' practice as a total was satisfactory, which improved post-training to be 83.0% of them had satisfactory practice. During follow-up, this percentage declined to be 75.4% with statistical differences were in pre, post, follows up. Conclusion: There was a statistical improvement related to risk management among nurses after the training strategy implementation. Recommendation:  health authorities should develop and implement clear policies for all health workers in hospitals and for staff nurses particularly to reduce risks in the workplace.