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327819

Cholesterol-lowering effects of Ginkgo biloba leaves or cassia tora seeds on hypercholesterolemic

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Last updated: 24 Dec 2024

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Abstract

This study looked at how Ginkgo biloba leaves (GB) and Cassia tora seeds affected hypercholesterolemic rats lipid profiles for eight weeks. Thirty six adult male rats were divided into two main groups. The first main group    (six rats) were fed a regular diet and used (as -ve control group). The second main group of 30 rats, fed on a high-cholesterol diet to induce hypercholesterolemia for 7 weeks, then was divided into five subgroups as follows: Subgroup (1) was fed a high-cholesterol diet and used as a positive control group. Subgroup (2 and 3) were given high-cholesterol diets that included supplements of 5% and 10% Gb leaves powder, respectively. Subgroup (4 and 5) were given high-cholesterol diets that included supplements of 5% and 10% powder from C. tora seeds, respectively. According to the obtained findings, liver enzymes, kidney functions and lipid profile were found to be significantly decreased (P≤0.05) while, HDL-C was noticeably increased by Gb leaves or C. tora seeds at the tested levels as compared to the positive control group. Furthermore, significantly increased in antioxidant enzymes (SOD and CAT) while, a decrease in MDA by Gb leaves or C. tora seeds supplementation at the tested levels in hypercholesterolemic rats. In conclusion that Gb leaves or C. tora seeds significantly reduced cholesterol levels while also improved liver enzymes, kidney functions and antioxidant enzyme. Therefore, Gb leaves or C. tora seeds may be recommended for hypercholesterolemic patients.

DOI

10.21608/pssrj.2023.227417.1257

Keywords

Ginkgo biloba leaves, Cassia tora seeds, Hypocholesteremia, Lipid profile, antioxidant status

Authors

First Name

ميرنا السيد ابراهيم

Last Name

عطية الشافعي

MiddleName

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Affiliation

كلية التربية النوعية -جامعة بور سعيد

Email

mernae284@gmail.com

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Orcid

-

First Name

اشرف

Last Name

عبد العزيز عبد المجيد

MiddleName

-

Affiliation

کلية الاقتصاد المنزلى - جامعة حلوان

Email

ashrafabdaziz@gmail.com

City

-

Orcid

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First Name

شيماء

Last Name

حسن نجم

MiddleName

-

Affiliation

قسم الاقتصاد المنزلى، كلية التربية النوعية، جامعة بورسعيد

Email

shimaa.hasan@spcd.psu.edu.eg

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-

Orcid

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Volume

22

Article Issue

22

Related Issue

44565

Issue Date

2023-10-01

Receive Date

2023-08-05

Publish Date

2023-10-01

Print ISSN

2536-9253

Online ISSN

2682-325X

Link

https://pssrj.journals.ekb.eg/article_327819.html

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https://pssrj.journals.ekb.eg/service?article_code=327819

Order

16

Type

المقالة الأصلية

Type Code

864

Publication Type

Journal

Publication Title

مجلة کلية التربية النوعية - جامعة بورسعيد

Publication Link

https://pssrj.journals.ekb.eg/

MainTitle

Cholesterol-lowering effects of Ginkgo biloba leaves or cassia tora seeds on hypercholesterolemic

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Article

Created At

24 Dec 2024