ABSTRACT:
Objective: The objective of this study is to evaluate and comparing the effect of Coral Nano Silver, Biomin, and Novamin kinds of toothpaste on remineralization of demineralized enamel considering the time factor. Materials and methods: one hundred and ten enamel slabs were prepared from the buccal and palatal enamel surface of the human maxillary premolar teeth. The prepared enamel samples were randomly divided into five main groups according to the type of remineralizing toothpaste. Each main treated group was further subdivided into 3 equal subgroups (n=10) according to the remineralization periods (7, 14, and 28 days). Data were statistically analyzed using SPSS® statistics version 20, F-test, (ANOVA) was used for normally distributed quantitative variables, to compare between more than two groups, all tests are two- tailed, and the level of significance was set P<0.05. Results: After remineralization, all samples showed a decrease in surface roughness and an increase in surface microhardness, which was significantly higher with coral calcium Nano silver toothpaste. Conclusion: Coral calcium Nanosilver toothpaste is a promising remineralizing agent by reducing enamel surface roughness and increasing surface microhardness.