Objectives: The aim of the present was to evaluate the effect of platelet rich fibrin and bio-oss for socket preservation.
Materials (Subjects): Thirty patients were divided randomly, into 3 groups: Group (A): include sockets which left to heal alone. Group (B): include sockets grafted with bio-oss. Group (C): include sockets grafted with bio-oss and PRF. Follow up: 1st and 7th day post operatively to evaluate patients clinically, and one ,six months for radiograph evaluation by CBCT.
Results:There were a minimum statistically significant reduction in bone height, width and density in group C, B than group A (control group). Group C which include sockets grafted with bio-oss and prf showed minimum reduction and best results in length, width, density and volumetric changes than group B.
Conclusion: Bio-oss bone either grafted with PRF or not is effective on healing process and decrease bone resorption than leaving socket to heal alone.
Keywords: Bio-oss, PRF, bone length, width.