Abstract:
Objective: Bone regeneration of periapical bone defects is a great challenge to the surgeon, especially in case of large bony defects. Various bone graft materials such as platelet-rich fibrin (PRF) and β-tricalcium phosphate (β-TCP) are used in periapical surgery to stimulate a new bone tissue formation. So, this study was carried out to evaluate and compare the effect of PRF, β-TCP, and combination of these materials as periapical bone defect filling materials on the resulted bone density, cavity height, and width by using cone beams computed tomography imaging.
Patients and methods: This study was conducted on twenty-four patients with bone defect resulting from periapical lesion, selected from the outpatient clinic of Al-Azhar University, Cairo (boys) and Sayed Jalal University Hospital with age group of 18 to 40 years. The Patients were divided equally into three groups: Group A: The defect was filled with PRF alone. Group B: The defect was filled with β-TCP alone. Group C: The defect was filled with combination of PRF/ β-TCP.
Results: The results of this study revealed that; significant increase in bone density, bony defect width and height in the three different studied groups after six months when compared to the baseline.
Conclusion: The treatment of the periapical bone defects with different bone graft materials helps to increase the bone density and reduce the bone defect dimensions. The uses of combination of PRF/ β-TCP in the treatment of preapical bone defect may contribute to more favorable and predictable bone formation at the grafted site.