This study was carried out to evaluate the chemical composition and sensory evaluation of Rusk containing physalis paste at ratio of 10% and 20%. There were no significant difrences between Physalis Rusk and control samples in the organoleptic properties. Also, in this study, healthy and nutritional values of Physalis Rusk was studied. Diabetic rats were fed on 5% Physalis Rusk (containing 10% and 20% physalis). Blood glucose, liver and kidney functions were determined in blood serum. Histopathalogical studies on liver, pancreas and kidney sections were carried out. Results showed that diabetic rats which fed on physalis Rusk had low blood glucose, total cholesterol, triglycerides and low density lipoprotein. While, high density lipoprotein was increased. Results revealed an improve in liver, pancreas and kidney of rats fed on physalis Rusk. Liver, pancreas and kidney sections of physalis Rusk rats were improved compared with control diabetic rats. From the foregoing results in the current work, it could be recommended to add physalis paste at a ratio of 10 or 20% during the manufacture of Rusk to get the healthy and nutritional benefits of this product.