Wheat is the most important crop in Egypt and the imports are large to fill the gap between production and consumption. Biofertilization is highly needed to help increasing the local production.N₂ fixers Azospirillum+Azotobacterbacteria, P-dissolver  Bacillus megaterium  bacteria and K-dissolver B. circulans  bacteria were assessed for wheat growth and nutrient uptake in 3 pot experiments (one for each nutrient) in  absence or  presence of nutrient-rich  chicken  manure (CM) applied at 10 g kg^-1.Increases in plant growth (45-day growth) of up to 50% occurred particularly in presence of CM. Sources of rock phosphate P and rock (feldspar) K were used to provide available P and K with the help of the biofertilizers and along with the organic manure. Soluble sources of N (ammonium sulphate), P (Ca-superphosphate) and K (K-sulphate) were included for comparisons. Practical implications indicate a strong proofs that using biofertilizers can contribute to sustainability in boosting wheat production.