352631

Proteinaceous Bacterial compounds isolated from different sources with multiple activities against cancer and microbial infection

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Basic and applied research of Microbiology

Abstract

In recent years, global health authorities have had to deal with two significant problems : the alarming number of people suffering from cancer and the rise of antimicrobial resistance (AMR).
Cancer is one of the major reasons for morbidity and mortality in the world while becoming a major concern of human health in the 21st century. In the year 2018, there were about 17.0 million new cases of cancer reported along with 9.5 million deaths worldwide due to cancer
Tremendous efforts and progress have been made towards finding a cure for cancer.
Another pandemic is hiding in plain sight. Antimicrobial resistance (AMR) is already a leading threat to global health and risks adversely affecting the environmental sustainability of the planet. The consequences of the continuing development and spread of AMR could be catastrophic AMR occurs when microbes such as bacteria, viruses, parasites and fungi are, or become, resistant to antimicrobial treatments to which they were previously susceptible. Antimicrobials are widely used in human and animal healthcare, and in crop and animal production

Currently, bacterial proteins and peptides are important as antiproliferative agents. Some of these are already used in cancer treatment, others are in human clinical trials or studied in vitro. In this study glutaminase enzyme has been studied as anticancer and antimicrobial agent.

DOI

10.21608/bfszu.2023.159388.1177

Keywords

Cancer, Antimicrobial resistance, bacterial proteins, glutaminase

Authors

First Name

Asmaa

Last Name

Mohamed ibrahim

MiddleName

Elsayed

Affiliation

Botany department, faculty of science, Zagazig University

Email

asmaaslama99@gmail.com

City

zagazig

Orcid

-

First Name

eman

Last Name

elariny

MiddleName

Youssef Tohamy

Affiliation

faculty of science zagazig university

Email

emanariny@yahoo.com

City

-

Orcid

-

First Name

Lina

Last Name

M.Abdel-Hafez

MiddleName

Jamil

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, October 6 University, October 6 city, Giza, EGYPT

Email

lina.jamil@ymail.com

City

-

Orcid

-

Volume

2024

Article Issue

1

Related Issue

47419

Issue Date

2024-04-01

Receive Date

2022-08-29

Publish Date

2024-04-01

Page Start

1

Page End

14

Print ISSN

1110-1555

Link

https://bfszu.journals.ekb.eg/article_352631.html

Detail API

https://bfszu.journals.ekb.eg/service?article_code=352631

Order

1

Type

Original Article

Type Code

838

Publication Type

Journal

Publication Title

Bulletin of Faculty of Science, Zagazig University

Publication Link

https://bfszu.journals.ekb.eg/

MainTitle

Proteinaceous Bacterial compounds isolated from different sources with multiple activities against cancer and microbial infection

Details

Type

Article

Created At

24 Dec 2024