Using pesticides (chemical control) is one of the most strategies that used in integrated pest management programs to keep pest infestations below significant levels, that will not negatively impact the crops. The susceptibility of the pest populations to pesticides reduces with time, causing resistance to the recommended pesticides. One of the best solutions to avoid this resistance is to rotate between several chemical groups with different mode of actions. In this study, evaluation of the efficacy of three pesticides belongs to different classes; Acetamiprid (neonicotinoids), Lambda (pyrethroids), and Plamic 5% (biocide) along with the recommended molluscicide, Newmyl (carbamate) were investigated against Monacha cartusiana under laboratory conditions at four concentrations (2, 4, 6, and 8%) and under field conditions at 8% concentration. The data revealed that; commercial pesticides showed high to moderate activity. Under laboratory conditions, Plamic 5%, and Lambda were the most active of tested compounds when compared with Newmyl. Where; Plamic 5%, and Lambda exhibited 100% mortality percentage at 4, 6, and 8 % concentrations after 3 days post-treatment. While, Newmyl recorded 100 % mortality percentage at 8 % concentration only after the same period. Under field conditions, Acetamiprid exhibited satisfactory activity when compared with Newmyl followed by Plamic 5%. The mean of the residual effect of Newmyl was 75.96 % while, Acetamiprid and Plamic 5% recorded 56.54, and 47.52 %, respectively.