Background: Patients undergoing craniotomy commonly experience impairments in both balance and cognitive function. Aim of the study: Was to evaluate the effect of training program on cognitive functions and balance ability among patients undergoing craniotomy. Subjects and Methods; Research Design: Quasi experimental research design was utilized to achieve the aim of the study through pre/posttest. Setting: The study was established in neurosurgery ICU of Accidental Hospital and neurosurgery outpatient clinics, Zagazig University Hospitals. Subjects: A purposive sample of 55 adult patients undergoing craniotomy during study periods. Tools of data collection: Four tools were utilized; Interviewing questionnaire, The Mini Mental State Examination scale, Berg Balance Scale, and Satisfaction level questionnaire. Results: A statistical significant improvement in all cognitive functions for studied patients regarding orientation, registration, attention and calculation, recall, and language was found post program with Mean ± SD 23.94±3.63. There was a statistical increase in mean scores of balance ability regarding standing, sitting, transfers, and turning post program than before. Also, 85.5% of studied patients were
satisfied with care provided after training program. Conclusion: The training program had an obvious positive effect on cognitive function and balance improvement among study patients which reflected then on increasing their satisfaction level regarding care provided. Recommendations: The training program should be available for all patients undergoing craniotomy. Moreover, nurses should participate in training program to improve cognitive functions and balance ability among patients undergoing craniotomy.