Background: Nurses are the largest human resource group and backbone of every health care system. Head nurses are the key to professional communication between the top management and staff nurses, their role is highly important in the success of healthcare organizations so this requires certain skills and practices are very important to increase nurses innovative work behavior. Aim: to assess the relation between leadership competencies and innovative work behavior of nurses. Subjects and Method: Research design: A descriptive correlation design was used to achieve the aim of this study. Setting: The study was conducted El- Sinbellawin General Hospital, Dakahlia, Egypt. Subjects: Simple random sample from nurses (n= 240), A convenient sample of (30) head nurses were selected. Tools: leadership competency scale and innovative work behavior scale, Results: (47.9%) of the studied nurses reported that head nurses had a high level of leadership competencies. While, (46.7%) of head nurses reported that nurses had a high level of innovative work behavior. Conclusion: there was statistically significant positive correlation between leadership competencies, innovative work behavior. Recommendations: Conduct workshops on innovative thinking and develop strategies to enhance nurses' level of innovative work behavior, As well administer continuous learning about modern and innovative ways of leadership to update and promote leadership competencies of head nurses.