Diseases epidemics associated with high death rates produce high economic fatalities in the aquaculture industry. Vitamin premix (VP) supplementation may bolster the immune response in Nile tilapia. Accordingly, we aim to find optimal feeding strategies to enhance farmed fish health and survival. Our study performed several biochemical, immunological, and histological analyses to assess the effect of VP supplementation in promoting growth performance-related parameters. The results revealed that different levels of VP could significantly enhance Nile tilapia growth, feed utilization, and survival. Moreover, the findings provided a comprehensive understanding of the temporal and treatment-dependent changes in metabolites and lysozyme activity, shedding light on the intricate physiological responses of Nile tilapia to varying VP levels in their diets. Our study offers innovative approaches to improve the well-being and longevity of cultivated Nile tilapia by providing a sustainable method for reducing the adverse effects of bacterial problems in aquaculture environments.
Keywords: Nile tilapia; Vitamin premix; Dietary supplementation; Aeromonas sobria