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Comparative Study between Intravenous Ketamine and Magnesium Sulphate for Prevention of Shivering Post-Intrathecal Anesthesia

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Last updated: 24 Dec 2024

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Abstract

Background: Spinal anesthesia is recognized for its ability to greatly hinder the body's ability to regulate temperature. It does this by suppressing the body's natural vasomotor and shivering reflexes, as well as by moving heat away from the central part of the body to the peripheral tissues.
Aim: This study aimed to contrast the efficiency of intravenous ketamine against Magnesium sulphate added to 100 ml saline to prevent shivering associated with spinal anesthesia.
Methods: This is a prospective, randomized, double blinded controlled work. The present study was performed on 180 patients admitted to Al-Azhar University Hospitals, undergoing different elective procedures utilizing spinal anesthesia. Each participant was ASA physical status I and II.
Results: A statistically significant reduction in the frequency of shivering [grade II or greater] in the two groups, group K [23.3%] and group M [40%] contrasted to the frequency of 51% in the control group. Incidence of shivering was insignificantly different Immediately after spinal anesthesia, 5min, 10min,15min and 90 min and was substantially lower in group K in contrast to group M and group C and was significantly reduced in group M in contrast to group C [P value<0.05]. These results suggest that both Ketamine and Magnesium sulphate substantially decrease the frequency of shivering contrasted to the control group. And also, both delay the onset of shivering [if it happen] by a considerable amount.
Conclusion: Administering Ketamine at a dosage of 0.5 mg/kg, diluted in 100 ml of normal saline, over a 10minute period as a preventive measure is more effective compared to administering Magnesium sulphate at a dosage of 50 mg/kg, diluted in 100 ml of normal saline, over a period of 10 minutes in managing shivering after spinal anesthesia.

DOI

10.21608/ijma.2024.307393.2008

Keywords

Ketamine, Magnesium sulphate, shivering, spinal, Anesthesia

Authors

First Name

Mohamed

Last Name

Mahmoud

MiddleName

Ali

Affiliation

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Al-Azhar University, Assiut, Egypt

Email

mohamedali.226@azhar.edu.eg

City

-

Orcid

0009-0009-1282-5628

First Name

Abdelrhman

Last Name

Haron

MiddleName

Ahmed

Affiliation

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Al-Azhar University, Assiut, Egypt

Email

doctorharon94@gmail.com

City

-

Orcid

-

First Name

Osama

Last Name

Ahmed

MiddleName

H.

Affiliation

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Al-Azhar University, Assiut, Egypt

Email

doc_sofyan@yahoo.com

City

-

Orcid

-

Volume

6

Article Issue

10

Related Issue

51761

Issue Date

2024-10-01

Receive Date

2024-07-26

Publish Date

2024-10-01

Page Start

4,984

Page End

4,989

Print ISSN

2636-4174

Online ISSN

2682-3780

Link

https://ijma.journals.ekb.eg/article_388622.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=388622

Order

7

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Comparative Study between Intravenous Ketamine and Magnesium Sulphate for Prevention of Shivering Post-Intrathecal Anesthesia

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Article

Created At

24 Dec 2024