Background: In terms of global disability and mortality, neurological illnesses are second only to cardiovascular disease. People over the age of 60 are disproportionately affected by the global epidemic of cognitive decline. Cognitive decline is predicted to rise as the world's population ages; thus, policymakers and governments should pay close attention.
Aim of the work: The research set out to measure the connection between weak hand grips and dementia in the elderly.
Patients and Methods: This was across sectional study; hundred participants, aged above sixty years are taken from Sayed Galal University Hospital. Hand grip strength [HGS] is measured by sphygmomanometer.
Results: There was a statistically significant [p-value < 0.001] decreased HGS in patients with impaired MMSE [median = 132, IQR = 117 – 160] when compared with patients of normal MMSE [median = 165.5, IQR = 146.25 – 186.5].
Conclusion:  This research established a connection between handgrip strength variations and mental performance. Our big longitudinal research found that weaker handgrips predicted worse cognitive function.