Beta
348298

Feasibility and Safety of Thyroid Tissue Auto-transplantation after Total Thyroidectomy for Simple Multinodular Goiter

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

Surgery

Abstract

Background: Total thyroidectomy is currently considered the modality of choice for treatment of benign thyroid disorders. After surgery the patient becomes dependent on replacement therapy for life, thyroid tissue auto-transplantation provides the chance to avoid the need for life-long replacement therapy and to avoid post-thyroidectomy hypothyroidism in non-compliant patients.
The Aim of the work: This work aimed to investigate the feasibility and safety of thyroid tissue auto-transplantation after total thyroidectomy for simple multinodular goiter.
Patients and Methods: This study was designed to be an observational prospective study, conducted on 30 patients who were diagnosed with simple multinodular goiter and were submitted for total thyroidectomy followed by thyroid tissue auto- transplantation.
Results: Postoperative hypocalcemia with range of serum calcium level from 7.6 to 8 mg/dl [normal value: 8.5 to 10.2 mg/dl] was found in six patients [20%], the final outcome one year after surgery showed that all the cases had a functioning viable transplanted thyroid tissue, but with different degrees of function, six cases [20%] had fully functioning implants [T3, T4, and TSH were normal during the hormonal analysis], 21 cases [70%] had minimally insufficient implants which had normal levels of thyroid hormones but they had a high level of TSH although the iodine scan showed viable functioning implants, and 3 cases [10%] had insufficient implants which had low levels of thyroid hormones and high level of TSH hormone.
Conclusion: Thyroid auto-transplantation is a safe and easy procedure that provides survival and function of the thyroid implants and offers promising results in the majority of the selected patients.

DOI

10.21608/ijma.2024.179887.1569

Keywords

Auto-transplantation, Total Thyroidectomy, Simple Multinodular Goiter

Authors

First Name

Mohamed

Last Name

El Madawy

MiddleName

G.

Affiliation

Department of General Surgery, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

m3dawy42@yahoo.com

City

Biala, kafr elsheikh

Orcid

Mohamed ElMadawy

First Name

Islam

Last Name

Elzahaby

MiddleName

-

Affiliation

Department of Surgical Oncology, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

islamabdouu2010@mans.edu.eg

City

mansoura

Orcid

0000-0003-2139-4451

First Name

Ayman

Last Name

Elwan

MiddleName

Mahmoud

Affiliation

Department of General Surgery, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

elwanetal@gmail.com

City

New Damietta

Orcid

-

First Name

Nagah

Last Name

Salem

MiddleName

Atwa

Affiliation

Department of General Surgery, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

nagahsalem123@gmail.com

City

Manzalah, Dakahlia

Orcid

-

Volume

6

Article Issue

1

Related Issue

46972

Issue Date

2024-01-01

Receive Date

2022-12-10

Publish Date

2024-01-01

Page Start

4,082

Page End

4,090

Print ISSN

2636-4174

Online ISSN

2682-3780

Link

https://ijma.journals.ekb.eg/article_348298.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=348298

Order

348,298

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Feasibility and Safety of Thyroid Tissue Auto-transplantation after Total Thyroidectomy for Simple Multinodular Goiter

Details

Type

Article

Created At

24 Dec 2024