348271

Procalcitonin, Erythrocyte Sedimentation Rate and C- Reactive Protein Index as A Predictor for Spontaneous Bacterial Peritonitis in Decompensated Cirrhotic Patients

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Internal Medicine

Abstract

Background: The most reliable way to diagnose Spontaneous bacterial peritonitis [SBP] is with a positive ascitic fluid culture for a pathogen. However, it is invasive method. Several studies had reported another noninvasive tool for the diagnosis of SBP.
The Aim of the work: the aim of the study is to evaluate the predictive value of PEC index in diagnosis of spontaneous Bacterial Peritonitis, which made by measurement of procalcitonin, ESR and CRP, which we called the PEC index as a predictive value in Decompensated liver disease ascites.
Patients and Methods: This study was carried on 120 patients with cirrhosis.  All patients were selected from Internal Medicine Department at Al-Azhar University Hospital New Damietta. All patients were divided into the following groups: Group [A] include: Forty [40] patients with decompensated cirrhosis having SBP. Group [B] include: Forty [40] patients with decompensated cirrhosis having sterile ascites. Group [c] include: Forty [40] patients with compensated cirrhosis without ascites.
Results: We found that PCT in 0.48ng/mL cutoff level had sensitivity of 86% and specificity of 92%. ESR in 30.5 cutoff level had sensitivity of 84% and specificity of 64.4%. CRP in 23.5 cutoff level had sensitivity of 88% and specificity of 75.6%. PEC in 25 cutoff level had sensitivity of 92% and specificity of 97.8%.
Conclusion: The PEC index is effective in diagnosis of spontaneous Bacterial Peritonitis, which made by measurement of procalcitonin, ESR and CRP, which we called the PEC index as a predictive value in Decompensated liver disease ascites.

DOI

10.21608/ijma.2024.184037.1583

Keywords

Procalcitonin, erythrocyte sedimentation rate, C- reactive protein, Liver cirrhosis

Authors

First Name

Ahmed

Last Name

Elnshar

MiddleName

-

Affiliation

Department of Internal Medicine, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

ahmedelnshar94@gmail.com

City

-

Orcid

-

First Name

Amin

Last Name

Hegazy

MiddleName

Mahmoud Amin

Affiliation

Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

ami@gmail.com

City

-

Orcid

-

First Name

Tarek

Last Name

Emran

MiddleName

Mustafa

Affiliation

Department of Clinical Pathology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

tarekemran@yahoo.com

City

-

Orcid

-

First Name

Mahmoud

Last Name

Berengy

MiddleName

Saad

Affiliation

Department of Internal Medicine, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

mahmoudberengy78@yahoo.com

City

-

Orcid

-

First Name

El Sayed

Last Name

Ibrahim

MiddleName

Abouzid

Affiliation

Department of Internal Medicine, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

elsayedabozeid@gmail.com

City

-

Orcid

-

Volume

6

Article Issue

1

Related Issue

46972

Issue Date

2024-01-01

Receive Date

2022-12-28

Publish Date

2024-01-01

Page Start

4,045

Page End

4,053

Print ISSN

2636-4174

Online ISSN

2682-3780

Link

https://ijma.journals.ekb.eg/article_348271.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=348271

Order

5

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Procalcitonin, Erythrocyte Sedimentation Rate and C- Reactive Protein Index as A Predictor for Spontaneous Bacterial Peritonitis in Decompensated Cirrhotic Patients

Details

Type

Article

Created At

24 Dec 2024