Background: Numerous researches indicate that being overweight or obese may change how accessory glands are structured and function. As a result, it could be valuable to examine chemical markers of accessory glands as a means of identifying these changes.
Aim of the work: This study aims at evaluating the effect of obesity on markers of accessory glands [seminal vesicles and prostate], epididymis and seminal parameters [volume, concentration, motility, morphology, viability] in infertile men.
Patients and Methods: This study is a comparative cross-sectional study that included 50 males complaining from infertility, who were divided in two groups according to BMI; control group: BMI [18-25 kg/m²] and case group: BMI ≥ 25 kg/m². Semen analysis and markers of accessory gland were analyzed for all patients.
Results: The semen volume, sperm count was significantly decreased in obese adults as compared to controls. The total motility, progressive motility ratio and ratio of immotile sperms all were affected among obese infertile men. Serum fructose, citric acid and alpha glucosidase levels were all affected among obese individuals with statistically significant difference [P= <0.001].
Conclusion: Obese men showed decreased sperm and prostatic function as compared with controls. Markers of oxidative stress are linked with progressive adiposity. So that, avoiding excessive body weight in infertile men at the appropriate time could lead to an improvement in both infertility and prostate disorders.