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Formulated Posterior Subtenon Triamcinolone Versus Triamcinolone Alone in The Management of Macular Edema Secondary to Non-Ischemic Retinal Vein Occlusions

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

Ophthalmology

Abstract

Background: Visual impairment, and even blindness, can result from Retinal Vein Occlusion [RVO], making it the second most common vascular disorder of the retina after diabetic retinopathy.
Aim of the Work: To evaluate the effectiveness of the posterior subtenon triamcinolone acetonide [PSTA] alone or formulated in the treatment of macular edema caused by central or branch non-ischemic retinal vein occlusions.
Patients and Methods: Our study included 78 patients, divided into two groups; Formulated PSTA group and PSTA alone group, each of them 39 patients. The NAGATA subtenon cannula was used to administer 40 mg of triamcinolone acetonide [TA] to both groups via the posterior subtenon channel.
Results: At one month, the BCVA improved from 0.4 [0.1 - 0.71] at the baseline to 0.80 [0.10-1.00] in the formulated group, unlike PSTA alone group which was no improvement. This was associated with a reduction in the CMT in the formulated group more than in the PSTA alone group. In the third month, the BCVA increased to 0.90 [0.20-1.00] in formulated group and remain constant in the sixth month. However, in PSTA alone group, the improvement in the BCVA started occurring in the third month which increases from 0.40 [0.10-0.90] at the baseline and the first month to 0.60 [0.20-1.00] in the third month and 0.80 [0.20-1.00] at sixth month. No elevation in the IOP in both groups.
Conclusion: We found that formulated TA is more efficacious than TA alone in improving BCVA and lowering CMT in patients with ME related to Non-Ischemic RVO when administered early in the disease process, without causing any elevation in intraocular pressure.

DOI

10.21608/ijma.2023.191761.1616

Keywords

Formulated PSTA, retinal vein occlusion, Subtenon, Triamcinolone, macular edema

Authors

First Name

Ehab

Last Name

Tharwat

MiddleName

-

Affiliation

Department of Ophthalmology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Email

ehabtharwat71@domazhermedicine.edu.eg

City

-

Orcid

0000-0002-5917-2929

Volume

5

Article Issue

1

Related Issue

40592

Issue Date

2023-01-01

Receive Date

2023-02-04

Publish Date

2023-01-01

Page Start

2,938

Page End

2,943

Print ISSN

2636-4174

Online ISSN

2682-3780

Link

https://ijma.journals.ekb.eg/article_292145.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=292145

Order

2

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Formulated Posterior Subtenon Triamcinolone Versus Triamcinolone Alone in The Management of Macular Edema Secondary to Non-Ischemic Retinal Vein Occlusions

Details

Type

Article

Created At

24 Dec 2024