Al-Moez Street is a remarkable tourist attraction that is open to many groups of visitors per day especially, after the government renovations to transform the street into an 'open-air' museum.  However, it is impossible for tourists to experience heritage resources without causing negative impacts to those resources. Literature revealed that tour guide interpretation is one of the main factors influencing tourists' behavior. however, very limited research has been conducted to investigate the relationship between tour guide interpretation, place attachment and sustainable behaviour. Therefore, study contributes to fill in some gaps in the literature regarding the relationship between tour guide's interpretation and place attachment and assessing whether sustainable behavior can be stimulated through the mediating role of place attachment or not. For this purpose, a questionnaire has been distributed among 240 local and foreign tourists who visited Al -Moez Street in guided tours. Results indicated that the sustainable behavior at cultural heritage sites can be stimulated through the mediating role of place attachment. The study recommends that the tourist Guide Syndicate should seek to improve tour guides' interpretation through education and trainings to upgrade their skills additionally, Site administrators should combine personal interpretation with non-verbal one for more sustainable heritage sites.